KONYA UNIVERSITY MERAM MEDICINE FACULTY EMERGENCY DEPARTMENT
KONYA UNIVERSITY MERAM MEDICINE FACULTY EMERGENCY DEPARTMENTA
KONYA UNIVERSITY MERAM MEDICINE FACULTY GENERAL SURGERY DEPARTMENT

INTRODUCTION:
Reversion of the anticoagulant effect of vitamin K antagonists (VKAs) in cases of symptomatic overdose, active bleeding episodes, or need for emergency surgery is the most important indication for human prothrombin complex concentrates (PCCs) and this effect of PCCs appears to be more complete and rapid than that caused by administration of fresh frozen plasma. CASE: A 80 year – man had a history of warfarin was admitted to emergency service due to abdominal pain. He had normal physical findings except abdominal signs. At time of 15.52, his laboratory results were PT, 74.5 second (11.0-15.0); INR, 9.16 (1.00-1.50). Abdominal ultrasonography showed two hematomas located on iliopsoas muscles. treatment of PCCs with 1250 IU and 10 mg Vitamin K1 were administered intravenously at the emergency department. At time of 18.30, his laboratory results were PT, 18.6 second; INR, 1.53 and he was stable clinically. At time of 18.30, his laboratory results were PT, 18.6 second; INR, 1.53 and he was stable clinically. RESULT: PCCs seem to be more efficient than FFPs in case of reversal of anticoagulant effect of VKAs. However, this patient group should be followed for thromboembolism.